Endocrine Abstracts

Objective: Adipocytokines appear to be important in regulating insulin sensitivity. The objective of this study was to compare the levels of adiponectin and leptin in lean, obese and obese diabetic (OD) postmenopausal female (PMF) subjects during 6 months follow-up of Metformin therapy (MT).Methods: We examined plasma levels of adiponectin and leptin in 26 OD PMF with a mean body mass index (BMI) of 36.6±1.8, 10 obese (BMI=35.9±2.2) and 10 lean...

Objective: Oxidative stress is developing by disequilibrium between antioxidative and oxidative mechanisms. In these conditions dysfunction of thyroid gland (TG) has been reported. It is related with deranged biosynthesis of thyroid hormones, in particular, with the absorption of iodine in thyrocytes. The objective of our investigation was to study the impact of oxidative stress on autoimmune diseases (AD) of TG.Methods: 38 patients [group 1 - with diffu...